How CBD Topicals Interact With the Skin

As integrative healthcare practitioners, you are often asked about CBD topicals and the skin. This article gives a brief textbook note on the skin's endocannabinoid system, explains what a CBD topical is, and covers practical points for your practice.

The Skin's Endocannabinoid System

The skin possesses its own endocannabinoid system (ECS), a cell-signaling network that includes endogenous cannabinoids and metabolic enzymes. This system plays a role in skin homeostasis, including cell proliferation and differentiation.

Definition: The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s, involved in regulating a range of functions and processes, including skin health.

What We Do Not Claim

Research into how plant cannabinoids such as CBD relate to the skin's endocannabinoid system is still ongoing. Kannaco topicals are topical products for the skin, so we do not claim that they act on that system or on any body process, or that they treat, cure or prevent any condition.

How CBD Topicals Are Described

A CBD topical is described by:

• Feel: Cooling, warming or cool-then-warm on the skin, depending on the formula.


• Texture and Format: A cream in an airless pump or a hands-free rollerball, with a clean, non-greasy finish.


• Skin Conditioning: Moisturizing ingredients in the base help soften, smooth and hydrate the skin.

Where CBD Topicals Fit in a Practice

In a practice setting, a CBD topical can be part of:

• Massage: Used as a glide during hands-on work.


• After Activity: Applied to areas such as the neck, shoulders, back or knees after a workout or a long day.


• Daily Self-Care: Taken home as part of a regular self-care routine.

Considerations for Clinical Practice

When offering CBD topicals in your practice, consider the following:

• Product Quality: Ensure products are third-party tested for purity and potency.


• Patient Education: Tell patients plainly what a CBD topical is, and share the ingredient list and lab report.


• Regulatory Compliance: Stay updated on local regulations regarding CBD use in clinical practice.

Frequently Asked Questions

For a selection of high-quality CBD topicals, visit our Topicals Collection.

Updated July 2, 2025

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.