Ingredient Transparency

The Book of Topical Ingredients

Every ingredient in every KannaCo topical — what it is, where it comes from, and exactly why we chose it. No filler. No mystery. Just full transparency.

8 min read 3 Products Covered 62 Unique Ingredients

Continue your education

Science

Topical CBD 101

How cannabinoids interact with skin receptors and the endocannabinoid system.
Comparison

CBD vs. CBG vs. Full Spectrum

Understanding the difference between cannabinoid types and which is right for your needs.
Reference

Glossary of Technical Terms

Plain-language definitions for every scientific term used across our formulations.
Cannabinoids

Cannabinoids

The functional hemp-derived compounds at the core of every KannaCo formula. These interact with the body's endocannabinoid system receptors in the skin and underlying tissue.

3 ingredients
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    CBD (Cannabidiol)

    Cannabidiol

    Non-intoxicating hemp-extracted cannabinoid. Solubilized via hyper-emulsion for uniform distribution throughout the formula. Present at 2,000mg per bottle in all three products.

    Why it matters

    The most studied hemp cannabinoid in topical research. At 20–22mg/mL, KannaCo delivers a clinically meaningful concentration — not a trace amount.

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    CBG (Cannabigerol)

    Cannabigerol

    Known as the "mother cannabinoid," CBG is the biosynthetic precursor to CBD, CBC, and THC. CB2 receptor affinity. Paired 1:1 with CBD in all three formulas at 2,000mg per bottle.

    Why it matters

    Rare in topicals at clinical concentration. Broadens the cannabinoid profile beyond CBD alone — a meaningful differentiator from single-cannabinoid products.

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    CBDV (Cannabidivarin)

    Cannabidivarin

    A naturally occurring minor cannabinoid present in the full-spectrum hemp extract used in CBD Cooling Cream. Trace concentration; contributes to the entourage effect.

    Why it matters

    Present only in Cooling Cream's full-spectrum extract. The entourage effect theory suggests minor cannabinoids working together may produce a more complete experience than isolates alone.

Terpenes

Terpenes

Aromatic compounds found naturally in hemp and other plants. In our formulas, terpenes serve dual roles: contributing to the sensory experience and supporting the activity of cannabinoids.

9 ingredients
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    Beta-Caryophyllene

    Beta-Caryophyllene

    A sesquiterpene found in hemp, black pepper, and cloves. Direct CB2 receptor agonist — the only terpene classified as a dietary cannabinoid. Earthy, spicy, woody aroma.

    Why it matters

    Uniquely bridges the terpene and cannabinoid worlds. Its CB2 receptor activity means it contributes to the formula's effect profile, not just its aroma.

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    Eugenol

    Eugenol

    Derived from clove oil. Warm, spicy aromatic compound that blends into the oil phase of the formula. Contributes to the warming sensory layer in Pro Cream.

    Why it matters

    Adds aromatic depth and a subtle warming note that complements the cooling agents — creating a more complex, layered sensory experience.

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    Limonene

    Limonene

    Citrus-derived monoterpene. Penetration enhancer that helps functional ingredients reach target tissue faster. Uplifting, bright citrus aroma.

    Why it matters

    Improves bioavailability of cannabinoids and other actives by temporarily loosening the skin barrier — a functional ingredient, not just a fragrance.

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    Eucalyptol (1,8-Cineole)

    Eucalyptol

    Found naturally in eucalyptus and rosemary. Activates TRPM8 cold receptors to reinforce the cooling sensation. Also functions as a penetration enhancer.

    Why it matters

    Works synergistically with menthol on the same cold receptor pathway — amplifying and extending the cooling experience without adding more menthol.

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    Bisabolol

    Bisabolol

    Derived from chamomile. One of the gentlest skin-soothing terpenes available. Anti-irritant, skin-soothing, and supports the absorption of other functional ingredients.

    Why it matters

    Reduces the potential for skin irritation from stronger functionals like menthol and camphor — making the formula more tolerable for sensitive users.

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    Alpha Pinene

    Alpha Pinene

    The most abundant terpene in nature. Sharp pine aroma. Skin-soothing and bronchodilator properties. Part of the Pro Roll-On's 100mg terpene infusion stack.

    Why it matters

    Contributes to the Roll-On's clean, sharp aromatic profile and supports the skin-soothing activity of the cannabinoid stack.

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    Linalool

    Linalool

    Found in lavender and over 200 plant species. Calming, floral-lavender aroma. Anti-anxiety and sedating properties. Part of the Pro Roll-On terpene infusion.

    Why it matters

    Adds a calming dimension to the Roll-On's sensory profile — balancing the intensity of high-concentration menthol and camphor.

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    Myrcene

    Myrcene

    The most abundant terpene in cannabis. Earthy, musky aroma. Muscle relaxant properties. Believed to enhance the permeability of cell membranes, supporting cannabinoid uptake.

    Why it matters

    May act as a "gateway" terpene — helping cannabinoids cross the blood-brain barrier and cell membranes more effectively.

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    Nerolidol

    Nerolidol

    A sesquiterpene with deep floral-woody aroma. Penetration enhancer and anti-fungal properties. Supports transdermal delivery of functional ingredients through the skin barrier.

    Why it matters

    Enhances the Roll-On's 90/100 Penetration Assist Index score by helping functionals move through the stratum corneum more efficiently.

Essential Oils

Essential Oils

Concentrated plant extracts that deliver the sensory signature of each formula — the cooling, warming, and aromatic experience that makes each product distinctly recognizable.

8 ingredients
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    Peppermint Oil

    Mentha Piperita (Peppermint) Oil

    One of the most effective natural cooling agents. Activates TRPM8 cold receptors alongside menthol. Supports local circulation and delivers an immediate, recognizable cooling sensation.

    Why it matters

    Complements menthol's TRPM8 activation — creating a broader, more sustained cooling response than menthol alone can achieve.

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    Camphor Oil

    Cinnamomum Camphora (Camphor) Bark Oil

    Activates TRPV1 receptors to create a deep warming-after-cooling sensation. Traditional use in topicals for muscle discomfort. 11% concentration in Pro Roll-On.

    Why it matters

    Creates the characteristic "cooling then warming" sensory arc — the TRPV1 activation follows the initial TRPM8 cooling for a layered, sustained experience.

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    Rosemary Leaf Oil

    Rosmarinus Officinalis (Rosemary) Leaf Oil

    Stimulates local circulation to support functional delivery of cannabinoids. Antioxidant properties protect the formula from oxidation. Adds an herbal, camphoraceous aromatic note.

    Why it matters

    Improved local circulation means cannabinoids and other functionals are more efficiently distributed to the target area after application.

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    Boswellia Oil

    Boswellia Carterii Oil

    Frankincense-derived botanical resin oil. Traditional use in Ayurvedic medicine for joint and tissue support. Adds aromatic depth and a warm, balsamic note to the formula.

    Why it matters

    One of the most historically referenced botanicals for joint comfort. Boswellic acids are the subject of ongoing research for their role in supporting tissue health.

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    Lavender Oil

    Lavandula Angustifolia (Lavender) Oil

    Calming, floral aromatic. Skin-soothing and skin-soothing properties. Bridges the clinical and sensory experience — reduces perceived intensity of stronger functionals.

    Why it matters

    Aromatherapy research supports lavender's role in reducing perceived discomfort and promoting relaxation — making the application experience more pleasant.

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    Eucalyptus Leaf Oil

    Eucalyptus Globulus Leaf Oil

    Cooling aromatic with a clean, clinical scent. Supports the cooling layer alongside menthol and peppermint. Respiratory freshness and a sense of immediate relief on application.

    Why it matters

    The "clinical clean" scent of eucalyptus signals efficacy to the user — a psychological reinforcement of the product's professional-grade positioning.

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    Capsicum Fruit Extract

    Capsicum Annuum Fruit Extract

    Derived from chili peppers. A warming agent that activates TRPV1 receptors. Supports local circulation and deep penetration of the formula. Exclusive to Pro Cream.

    Why it matters

    Creates the characteristic warming sensation that defines Pro Cream's deep-tissue profile. Works with camphor to produce a sustained warming layer after the initial cooling.

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    Orange Peel Oil

    Citrus Sinensis (Orange) Peel Oil

    Cold-pressed from orange peel. Bright, uplifting citrus aromatic note. Adds a mood-lifting top note to the Cooling Cream's sensory profile. Exclusive to CBD Cooling Cream.

    Why it matters

    Citrus aromatics are clinically associated with mood elevation and reduced perceived discomfort — a subtle but meaningful addition to the Cooling Cream experience.

Botanicals

Botanical Extracts

Plant-derived extracts with centuries of traditional use and growing bodies of modern research. These ingredients form the botanical depth layer of each formula.

10 ingredients
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    Arnica Montana

    Arnica Montana Flower Extract

    One of the most clinically referenced botanicals for topical muscle and joint support. Traditional use for bruising, muscle soreness, and post-activity recovery. Exclusive to Pro Cream.

    Why it matters

    Arnica is the gold standard botanical for sports recovery topicals. Its inclusion in Pro Cream directly supports the deep-tissue, post-activity recovery positioning.

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    Aloe Vera

    Aloe Barbadensis Leaf Juice

    The primary base carrier of CBD Cooling Cream. 97% water content delivers immediate cooling on contact. Soothing, hydrating, and skin-soothing. Supports the 75/100 sensitive skin score.

    Why it matters

    Using aloe as the base (instead of water) means every application delivers an immediate cooling sensation before the menthol even activates — a true layered cooling system.

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    Cat's Claw

    Uncaria Tomentosa Extract

    Rainforest-derived botanical adaptogen from the Amazon basin. Traditional use in South American herbal medicine for joint support and immune function. Exclusive to CBD Cooling Cream.

    Why it matters

    Contributes to the Cooling Cream's 97/100 plant-based ingredient score and adds a rare, premium botanical to the formula that most competitors don't include.

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    Chamomile

    Chamomilla Recutita (Matricaria) Flower Extract

    Contains azulene, one of the most effective natural skin-soothing compounds. Soothing botanical with a long history of use for sensitive skin. Supports the 75/100 sensitive skin compatibility score.

    Why it matters

    Azulene is formed during steam distillation of chamomile and is responsible for its distinctive blue color and potent skin-soothing activity.

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    Calendula

    Calendula Officinalis Flower Extract

    Marigold-derived botanical with soothing and skin-comfort properties. Traditional use for skin repair and wound healing support. Supports gentle, daily-use positioning of Cooling Cream.

    Why it matters

    Calendula is one of the most trusted botanicals in natural skincare for a reason — it soothes without sensitizing, making it ideal for a formula designed for daily use.

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    Lavender Extract

    Lavandula Angustifolia (Lavender) Extract

    Liquid extract form of lavender — distinct from lavender essential oil. Calming, skin-soothing, and aromatic. Dual-form delivery (extract + oil) in Cooling Cream for a more complete lavender profile.

    Why it matters

    Using both lavender extract and lavender oil delivers the water-soluble and oil-soluble components of lavender — a more complete botanical profile than either form alone.

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    Dandelion Extract

    Taraxacum Officinale (Dandelion) Extract

    Rich in antioxidants including vitamins A, C, and K. Botanical antioxidant that supports skin health and formula stability. Adds to the 97/100 plant-based ingredient score.

    Why it matters

    Dandelion's antioxidant profile helps neutralize free radicals that can degrade both the formula and the skin — supporting long-term skin health with regular use.

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    Cucumber Extract

    Cucumis Sativus (Cucumber) Fruit Extract

    High water content delivers a cooling, hydrating effect on contact. Skin-refreshing botanical that reinforces the Cooling Cream's cooling layer. Antioxidant and skin-soothing properties.

    Why it matters

    Adds a third layer of cooling to the formula (alongside aloe and menthol) — contributing to the Cooling Cream's 92/100 cooling layer score.

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    Geranium Flower Extract

    Pelargonium Graveolens Flower Extract

    Rose-like aromatic with skin-toning and antioxidant properties. Balancing aromatic that bridges the floral and herbal notes in the Cooling Cream's complex scent profile.

    Why it matters

    Contributes to the Cooling Cream's balanced, non-clinical aroma — making it more appealing for daily use without the harsh medicinal scent of high-menthol products.

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    Melissa (Lemon Balm)

    Melissa Officinalis Leaf Extract

    Lemon balm extract with calming aromatic and antiviral properties. Skin-soothing with a gentle lemon-herbal scent. Adds a subtle herbal note to the Cooling Cream's sensory profile.

    Why it matters

    Melissa's calming properties complement the lavender and chamomile in the formula — creating a cohesive botanical calming layer that supports the sensitive skin positioning.

Carrier Oils

Carrier Oils

The lipid vehicles that transport functional ingredients into the skin. Carrier oils determine absorption speed, skin feel, and the overall elegance of the application experience.

5 ingredients
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    Jojoba Seed Oil

    Simmondsia Chinensis (Jojoba) Seed Oil

    Technically a liquid wax, not an oil. Structurally similar to human sebum — the skin recognizes it as its own. Non-comedogenic, fast-absorbing, and an excellent absorption enhancer.

    Why it matters

    Because jojoba mimics sebum, the skin doesn't try to compensate by producing more oil — making it ideal for all skin types, including oily and acne-prone skin.

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    Caprylic/Capric Triglyceride

    Caprylic/Capric Triglyceride

    Derived from coconut oil. The lightest carrier in the Pro Cream formula. Extremely fast absorption with a silky, non-greasy skin feel. Excellent solvent for cannabinoids and lipophilic functionals.

    Why it matters

    Enables Pro Cream to absorb quickly despite its rich texture — the fast-absorbing carrier prevents the greasy residue that would otherwise compromise clinical use.

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    Evening Primrose Oil

    Oenothera Biennis (Evening Primrose) Oil

    Rich in gamma-linolenic acid (GLA), an essential omega-6 fatty acid. Supports skin barrier function and repair. Primary contributor to the Cooling Cream's 72/100 barrier support score.

    Why it matters

    GLA is a precursor to skin-soothing prostaglandins — making evening primrose oil a functional ingredient for skin health, not just a texture agent.

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    Sesame Seed Oil

    Sesamum Indicum (Sesame) Seed Oil

    Natural UV-protective properties. Rich in antioxidants (sesamol and sesamin). Adds richness and emolliency to the Cooling Cream formula. Traditional use in Ayurvedic topical preparations.

    Why it matters

    One of the few carrier oils with documented UV-protective properties — a bonus benefit for a product used on exposed areas like hands, neck, and shoulders.

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    Shea Butter

    Butyrospermum Parkii (Shea) Butter

    Rich in fatty acids (oleic, stearic, linoleic) and vitamins A and E. Deep emollient and barrier support. Primary contributor to the Cooling Cream's 72/100 hydration and barrier scores.

    Why it matters

    Shea butter's fatty acid profile closely matches the skin's natural lipid barrier — making it one of the most effective natural emollients for long-term skin health.

Functional Agents

Functional Agents

The functional workhorses of each formula — ingredients with specific, measurable actions on the skin and underlying tissue that drive the primary sensory and formula experience.

4 ingredients
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    Menthol

    Menthol

    Primary cooling agent in all three formulas. Activates TRPM8 cold receptors in the skin to create an immediate, powerful cooling sensation. 15% concentration in Pro Roll-On — one of the highest in any OTC topical.

    Why it matters

    Menthol doesn't actually lower skin temperature — it tricks the nervous system into perceiving cold by activating the same receptors that respond to actual cold. This is why the cooling sensation is immediate and powerful.

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    Hyaluronic Acid

    Sodium Hyaluronate (Hyaluronic Acid)

    A naturally occurring polysaccharide that can hold up to 1,000× its weight in water. Deep skin hydration and moisture retention. Supports cannabinoid delivery through well-hydrated skin tissue.

    Why it matters

    Hydrated skin is more permeable to functional ingredients. Hyaluronic acid creates the optimal skin environment for cannabinoid absorption — a functional benefit, not just a cosmetic one.

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    MSM (Methylsulfonylmethane)

    Methylsulfonylmethane

    Organic sulfur compound. Penetration enhancer and skin-soothing agent. Supports the Pro Roll-On's 90/100 Penetration Assist Index. Helps functionals reach target tissue faster after application.

    Why it matters

    MSM is one of the most well-researched natural penetration enhancers. Its inclusion in the Roll-On directly supports the "rapid sensory engagement" positioning of the product.

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    Allantoin

    Allantoin

    Derived from comfrey root. Skin-calming, promotes skin cell turnover, and supports barrier repair. Accelerates healing of minor skin irritation. Gentle enough for daily use on sensitive skin.

    Why it matters

    Allantoin counterbalances the potential irritation from high-concentration functionals like menthol and camphor — making the formula suitable for sensitive skin and daily use.

Skin Conditioners

Skin Conditioners & Vitamins

Ingredients that protect, nourish, and maintain the health of the skin itself — ensuring that regular use of these formulas supports long-term skin wellness, not just immediate relief.

3 ingredients
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    Vitamin E (Tocopherol)

    Tocopherol (Vitamin E)

    Fat-soluble antioxidant that protects both the skin and the formula from oxidative degradation. Skin conditioning and barrier support. Present in all three formulas as a dual-function ingredient.

    Why it matters

    Vitamin E neutralizes free radicals that can degrade cannabinoids in the formula — protecting potency over the product's 24-month shelf life.

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    Oat Kernel Flour

    Avena Sativa (Oat) Kernel Flour

    Colloidal oat — clinically proven for eczema and sensitive skin management. Skin calming, anti-itch, and barrier-supporting. Contributes to the sensitive skin compatibility of both cream formulas.

    Why it matters

    Colloidal oat is FDA-approved as a skin protectant — one of the few natural ingredients with that designation. Its inclusion signals a commitment to genuine skin health, not just relief.

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    Glycerin (Vegetable)

    Glycerin

    Humectant that draws moisture from the air into the skin. Standard in pharmaceutical-grade topicals. Plant-derived in all KannaCo formulas. Supports skin hydration and formula texture.

    Why it matters

    Glycerin creates a moisture reservoir in the upper layers of the skin — ensuring that the skin remains hydrated and receptive to functional ingredients between applications.

Emulsifiers

Emulsifiers, Stabilizers & Texture Agents

The structural engineers of the formula. These ingredients hold oil and water together, create the signature texture of each product, and ensure stability and consistency from the first pump to the last.

9 ingredients
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    Aristoflex AVC

    Aristoflex AVC

    Advanced polymer-based emulsion stabilizer and rheology modifier. Creates the luxuriously smooth, non-greasy texture that defines both cream products. Enables the hyper-emulsion delivery of cannabinoids.

    Why it matters

    Aristoflex AVC is a premium cosmetic polymer used in high-end skincare. Its inclusion is a direct contributor to the "luxuriously smooth" texture that differentiates KannaCo from basic CBD creams.

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    Dimethicone

    Dimethicone

    Silicone-based slip agent. Creates the smooth, non-sticky finish that allows the formula to spread evenly without dragging. Glide enhancer for clinical application techniques.

    Why it matters

    Dimethicone is what creates the "clean finish" that makes Pro Cream compatible with IASTM tools and kinesiology tape — a critical requirement for clinical use.

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    Xanthan Gum

    Xanthan Gum

    Natural fermentation-derived polysaccharide. Emulsion stabilizer and viscosity control agent. Maintains formula integrity across temperature changes and ensures consistent texture throughout shelf life.

    Why it matters

    Xanthan gum prevents ingredient separation — ensuring the first pump delivers the same formula as the last pump, regardless of storage conditions.

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    Cetearyl Alcohol

    Cetearyl Alcohol

    A fatty alcohol (not drying like ethyl alcohol). Emulsifier, emollient, and thickener. Creates the stable oil-in-water emulsion structure of the cream. Adds body and richness to the texture.

    Why it matters

    Despite the word "alcohol," cetearyl alcohol is a moisturizing ingredient — it's derived from coconut or palm oil and is safe for sensitive skin.

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    Cetyl Alcohol

    Cetyl Alcohol

    Fatty alcohol emollient and thickener. Adds body and richness to the cream texture. Works alongside cetearyl alcohol to create the stable emulsion structure of the cream formulas.

    Why it matters

    The combination of cetyl and cetearyl alcohol creates a more stable, richer emulsion than either alone — contributing to the "luxuriously smooth" texture of both cream products.

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    Glyceryl Stearate SE

    Glyceryl Stearate SE

    Self-emulsifying emulsifier derived from glycerin and stearic acid. Creates stable oil-in-water emulsions. Essential for the uniform distribution of cannabinoids throughout the formula.

    Why it matters

    The "SE" (self-emulsifying) designation means it creates stable emulsions without additional emulsifiers — simplifying the formula while maintaining stability.

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    Stearic Acid

    Stearic Acid

    Naturally derived saturated fatty acid. Emulsifier, skin conditioning agent, and formula stabilizer. Contributes to the Cooling Cream's smooth, stable texture and its compatibility with sensitive skin.

    Why it matters

    Stearic acid is a component of the skin's natural lipid barrier — its presence in the formula helps the cream integrate with and support the skin's own protective layer.

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    Isopropyl Palmitate

    Isopropyl Palmitate

    Lightweight ester that improves spreadability without greasiness. Skin-feel enhancer and absorption modifier. Contributes to the Cooling Cream's non-greasy, clean finish.

    Why it matters

    Isopropyl palmitate creates the "glide without grease" texture that allows the Cooling Cream to spread easily over large areas without leaving a residue.

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    Hydroxyethylcellulose

    Hydroxyethylcellulose

    Cellulose-derived thickener and film-forming agent. Creates the specific viscosity needed for the Pro Roll-On delivery system — thick enough to coat the rollerball, thin enough to flow smoothly.

    Why it matters

    The 95/100 Applicator Synergy score of Pro Roll-On is partly due to this ingredient — it creates the precise viscosity that makes the rollerball delivery system work as intended.

Preservatives

Preservatives, Solvents & Chelating Agents

The safety and stability layer of every formula. These ingredients prevent microbial contamination, extend shelf life, and ensure that every application delivers the same quality as the first.

6 ingredients
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    Phenoxyethanol + Ethylhexylglycerin

    Phenoxyethanol (and) Ethylhexylglycerin

    Industry-standard broad-spectrum preservative system. Paraben-free. Globally approved for cosmetic use. Prevents bacterial, fungal, and yeast contamination across the 24-month shelf life.

    Why it matters

    This combination is considered the gold standard paraben-free preservative system — effective at low concentrations, gentle on skin, and approved by all major global cosmetic regulatory bodies.

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    Tetrasodium EDTA

    Tetrasodium EDTA

    Chelating agent that binds metal ions in the formula. Prevents metal-catalyzed oxidation of functional ingredients. Boosts preservative efficacy and extends shelf life.

    Why it matters

    Metal ions from water and packaging can catalyze the degradation of cannabinoids and other functionals. Tetrasodium EDTA neutralizes these ions — protecting potency over time.

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    Propanediol

    Propanediol

    Plant-derived (corn) humectant and solvent. Gentler alternative to propylene glycol. Supports skin hydration, acts as a penetration enhancer, and helps dissolve functional ingredients uniformly.

    Why it matters

    Choosing propanediol over propylene glycol reflects KannaCo's commitment to cleaner ingredients — same function, better skin compatibility, and plant-derived sourcing.

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    Propylene Glycol

    Propylene Glycol

    Pharmaceutical-grade humectant and solvent. Used in the Pro Roll-On liquid system as a penetration enhancer and to maintain the precise viscosity needed for rollerball delivery.

    Why it matters

    In a liquid roll-on system, propylene glycol's solvent properties are essential for keeping high-concentration functionals like menthol (15%) fully dissolved and evenly distributed.

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    Alcohol Denat. (SD Alcohol 40)

    Alcohol Denat.

    Denatured alcohol used as a fast-evaporating carrier in the Pro Roll-On liquid system. Creates the quick-set, clean dry-down finish. Enhances initial penetration of functionals on contact.

    Why it matters

    The rapid evaporation of alcohol is what creates the Roll-On's signature "quick-set finish" — allowing users to apply and move immediately without waiting for the formula to absorb.

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    Aqua (Deionized Water)

    Aqua (Deionized Water)

    The primary base of all three formulas. Deionized to remove mineral impurities that could destabilize the emulsion or react with functional ingredients. The foundation of every oil-in-water emulsion.

    Why it matters

    Deionization is a critical quality step — mineral impurities in water can catalyze ingredient degradation and reduce shelf life. Using deionized water is a mark of pharmaceutical-grade manufacturing.

Want to understand the science behind these ingredients?

Topical CBD 101 — The Science CBD vs. CBG vs. Full Spectrum Glossary of Technical Terms