✓ 0.0% THC
Pro Cream
Pro Cream is designed to support areas of muscle, joint, and nerve-related discomfort u...
Shop Targeted Care & Comfort
Targeted Relief. Trusted Results.
Professional-grade CBD topicals recommended by 500+ licensed practitioners nationwide — engineered for adults who need real, lasting support.
- 25K+ Customers served
- 850+ Clinics nationwide
- 4.9★ Average review rating
Advanced Topical CBD Formulations
Professional-Grade Topical CBD
3 product3
The Solution
Kannaco's Advanced Formulation Technology
Kannaco's topical formulations are built on pharmaceutical-grade delivery science — the same principles used in transdermal drug delivery research — adapted specifically for cannabinoid molecules.
Nano-Emulsification
CBD and CBG are processed into nano-sized droplets (50–200nm) using high-pressure homogenization. This dramatically increases surface area and aqueous compatibility, enabling penetration through the stratum corneum's lipid matrix.
Penetration Enhancer System
A proprietary blend of pharmaceutical-grade penetration enhancers — including terpene-based compounds — temporarily disrupts the stratum corneum's lipid structure, creating transient pathways for cannabinoid molecules.
Optimal Log P Adjustment
The formulation matrix is engineered to shift the effective Log P of the cannabinoid complex from ~6.3 to the optimal 1–3 range for transdermal penetration, without compromising bioactivity.
Sustained-Release Matrix
A polymer-based sustained-release matrix controls the rate of cannabinoid release at the application site.
Formulation Comparison
Standard Topical
- Sits on skin surface
- <2% dermal absorption
- 2–3 hour effect window
- No receptor-level activity
Kannaco Formulation
- Reaches dermis & subcutaneous tissue
- 8–12× higher penetration
- 6–8 hour sustained release
- CB1/CB2 receptor engagement
8–12×
greater dermal penetration depth versus standard CBD topical formulations in independent testing
What's Inside
Not All CBD Is the Same.
KannaCo formulas combine multiple cannabinoids and terpenes — each with a distinct role in the body. Here's exactly what's in every bottle and why it matters.
CBD
20mg/mL
Cannabidiol (CBD)
Cannabis Sativa Extract / Cannabidiol — CAS #13956-29-1
The primary active cannabinoid in all KannaCo formulas. CBD is a non-intoxicating hemp-derived compound with documented affinity for CB2 receptors in peripheral tissue. At 20mg per mL, every pump delivers a clinically meaningful topical dose — far above the trace amounts found in most over-the-counter CBD products.
CBG
20mg/mL
Cannabigerol (CBG)
Cannabigerol — CAS #25654-31-3
Often called the 'mother cannabinoid' — CBG is the biosynthetic precursor to CBD, THC, and CBC. It is rare to find CBG in topicals at this concentration. CBG has documented affinity for both CB1 and CB2 receptors.
β-Caryo
β-Caryophyllene
Beta-Caryophyllene — CAS #87-44-5
A sesquiterpene found naturally in hemp, black pepper, and cloves. β-Caryophyllene is the only terpene known to directly and selectively bind CB2 receptors — making it a functional cannabinoid in its own right. At 20mg/mL, it contributes meaningfully to the formula's CB2 receptor engagement alongside CBD and CBG.
Cannabinoid Presence by Product
| Cannabinoid / Terpene | Pro Cream | Pro Roll-On | CBD Cooling Cream |
|---|---|---|---|
| CBD (Cannabidiol) | |||
| CBG (Cannabigerol) | Trace | ||
| CBDV (Cannabidivarin) | — | — | Trace |
| Terpene Infusion | |||
| Δ9-THC | 0.0% (THC-Free) | 0.0% (THC-Free) | <0.3% (Full Spectrum) |
| Total Cannabinoids per Bottle | Over 4,000mg (COA Verified) | Over 4,000mg (COA Verified) | ~4,843mg (COA verified) |
| Lab Verified (SC Labs) |
