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CBD Cooling Cream

Experience a new standard in topical relief with CBD Cooling Cream—crafted with full-spectrum hemp extract for those who demand quality, purity, and results they can feel. Infused with naturally occurring CBD, CBDV, CBG, and compliant trace Δ9-THC (<0.3%), this luxuriously smooth cream delivers a refreshing medium cooling sensation that builds gently, peaks in minutes, and fades without harshness.

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Product Benefits

How it Works

Practitioner Reviews

"The most effective on the market! I’ve used several different CBD creams in my clinic and this one comes out on top by far. My patients will even request it! The best customer service too. Great company and great product."

Renee T.

Waltham Holistic Clinic

"Our patients love this product! We do too! As the person that receives the product, I appreciate the care in packing the boxes."

Dr. Eric P., D.C.

Fuhr Chiropractic Clinic

"Flying off the shelf! We love it, our patients love it! We're having a hard time keeping enough on hand!"

Dr. Rick S., DC

Activate Chiropractic

"My patients and I love this stuff!"

Lellani H. Acu

Jasmine Pearl Acupuncture

"Kannaco reached out and although I receive interest from many companies, my instincts led me to give them a shot, and they haven’t disappointed. I’ve tried many others and quite honestly, through patient feedback Kannaco has proved to be the best."

Dr. Tony W. D.A.O.M, PhD

Acupuncture Zen in Delray Beach, FL

"Being a compound pharmacy, our profession is working with patients and their primary care physicians to fit their specific needs. Kannaco has proven to be a valuable part of that equation as a relief option that my patients continue to come back for."

Dr. Rachel D., PharmD, R.P.

InnovativeRx in Kearney, NE

"The Kannaco Pro Roll-on is my go-to post treatment with patients. This is great for shoulders, neck and lower back. I love how quickly the product works. Not only for patient use but one of my favorites for personal use as well."

Dr. Sam W., D.C., ART, TPI

Fix Medical Group in San Diego, CA

"Excellent Product!. This is an amazingly effective CBD +CBG cream.

Dr. Debbie N., D.C.

Carlsbad, CA

"Excellent Product!. This is an amazingly effective CBD +CBG cream.

Dr. Debbie N., D.C.

Carlsbad, CA

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How it Works

CBD Cooling Cream

CBD Cooling Cream engages the skin through three complementary pathways—precise delivery, sensory modulation, and endocannabinoid system (ECS) interaction—working together to provide a localized, layered effect.

Targeted Delivery & Skin Retention

The formulation begins with a hydrating aloe base paired with humectants for smooth application. A supportive oil phase—featuring medium-chain triglycerides, isopropyl palmitate, jojoba, shea, and dimethicone—establishes a breathable barrier on the surface. This film reduces evaporation while holding cannabinoids and cooling actives at the skin interface, extending their presence where receptors are most concentrated. Penetration aids assist lipid-soluble ingredients in moving into the skin’s lipid layers while avoiding systemic uptake.

The Cooling Response

Strategically layered cooling agents work in tandem to trigger nerve-level sensory modulation. By activating thermoreceptor pathways, the blend produces an immediate cooling sensation while reinforcing local comfort, complementing the delivery properties described above.

Cannabinoid and Botanical Integration

Full-spectrum hemp extract serves as the lead active, with CBD supported by trace levels of THC, CBG, CBDV, and the terpene β-caryophyllene. CBD indirectly engages CB1/CB2, influences TRP channels, and supports oxidative balance via PPAR-γ. β-Caryophyllene selectively binds CB2 receptors on immune cells, while the suite of minor cannabinoids widens receptor activity. Added botanicals—aloe, oat, allantoin, hyaluronate, shea, jojoba, and vitamin E—contribute to barrier resilience, ease skin reactivity, and support suppleness under stress.

Together, these mechanisms promote a professional-grade topical experience that is fast-acting, balanced, and non-psychoactive, making it well-suited for local relief applications.

Full Spectrum

CBD (Cannabidiol) Concentration

Full Ingredients

Aloe Barbadensis Leaf Juice, Aqua (Deionized Water), Cannabis Sativa Extract, Caprylic/Capric Triglyceride, Isopropyl Palmitate, Camphor, Glyceryl Stearate SE, Cetyl Alcohol, Stearic Acid, Glycerin, Simmondsia Chinensis (Jojoba) Seed Oil, Menthol, Cannabigerol, Propanediol, Butyrospermum Parkii (Shea) Butter, Phenoxyethanol (and) Ethylhexylglycerin, Xanthan Gum, Avena Sativa (Oat) Kernel Flour, Allantoin, Tocopherol, Dimethicone, Phenoxyethanol, Aristoflex AVC, Beta-Caryophyllene, Sodium Hyaluronate (Hyaluronic Acid), Eugenol, Ethylhexylglycerin, Uncaria Tomentosa Extract (Cat's Claw), Oenothera Biennis (Evening Primrose) Oil, Chamomilla Recutita (Matricaria) Flower Extract, Calendula Officinalis Flower Extract, Lavandula Angustifolia (Lavender) Extract, Pelargonium Graveolens Flower Extract, Sesamum Indicum (Sesame) Seed Oil, Melissa Officinalis Leaf Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Boswellia Carterii Oil, Lavandula Angustifolia (Lavender) Oil, Eucalyptus Globulus Leaf Oil, Mentha Piperita (Peppermint) Oil, Taraxacum Officinale (Dandelion) Extract, Citrus Sinensis (Orange) Peel Oil, Cucumis Sativus (Cucumber) Fruit Extract.

What is Full spectrum CBD?

Full Spectrum CBD contains the plant’s full range of cannabinoids (including trace THC ≤0.3%), terpenes, flavonoids, and other phytonutrients, maintaining the natural chemical profile of hemp for an “entourage effect.”

How does Full Spectrum CBD absorb through the skin?

The primary functional ingredients in our Pro Cream deep tissue formulation are a 1:1 ratio of CBD (Cannabidiol) and CBG (Cannabigerol), two non-intoxicating cannabinoids derived from hemp. A terpene profile with a Beta-Caryophyllene baseline for TRP channel receptor modulation along with Eugenol, and Eucalyptol.

These work in tandem, helping to calm soreness and support recovery in the applied area. The formula is also enriched with proven botanical functional ingredients like arnica, menthol, and camphor, which provide soothing herbal relief and a mild cooling/warming sensation. In addition, a blend of essential oils (including peppermint, lavender, eucalyptus, rosemary, and Boswellia) offers a pleasant natural aroma and skin-calming benefits.

Skin-nourishing elements such as jojoba oil, glycerin, oat extract, and hyaluronic acid are included to moisturize and protect the skin during treatment. Every ingredient is chosen to maximize therapeutic effect while being gentle on skin.

What is Skin Retention?

Pro Cream deep tissue is formulated to meet clinical standards. It contains zero THC (0.0%), ensuring no psychoactive effects and broad legal compliance. Its cannabinoid content is relatively very high (totaling 4,000 mg of CBD+CBG per 100 mL), far above typical retail CBD creams.

The formula is also dermatologist-tested and suitable for sensitive skin, whereas ordinary creams might use harsh additives. Pro Cream Deep Tissue is made in an FDA-registered, cGMP-compliant facility and is MoCRA-registered (in compliance with the Modernization of Cosmetics Regulation Act), with LegitScript certification attesting to its safety and legitimacy.

Clinicians will notice its elegant texture – rich enough to provide excellent coverage but designed to absorb quickly without a greasy residue, so it won’t leave the skin oily or stain linens. In short, this product distinguishes itself by its high potency, rigorous quality standards, and professional-friendly, non-greasy formulation.

What is a TRP Channel?

Transient Receptor Potential (TRP) channels are sensory ion channels in nerve and skin cells that detect temperature, pressure, and chemical signals, influencing sensation and cellular responses.

What are TRPV3 Channels?

TRPV3 channels respond to mild warmth and select botanical compounds, modulating skin sensation, barrier function, and keratinocyte activity.

What is PPAR-γ?

Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a nuclear receptor in skin cells that influences lipid production, barrier function, and anti-inflammatory pathways when activated by certain cannabinoids and lipids.

Certified Full Spectrum CBD Cream

CBD Cooling Cream Product Data

Certified CBD Cream

Cellular Modulation Map

A quick-reference chart that links the functional ingredients in CBD Cooling Cream to their associated TRP channels, cannabinoid receptors, and key peripheral skin cells—illustrating how cannabinoids, terpenes, and botanicals collectively influence sensory perception, cellular activity, and barrier function.

Full Spectrum CBD

CBD – TRPV1/TRPA1/TRPM8 modulation; 
indirect CB1/CB2; PPAR-γ activation.

Delta-9 THC (<0.3%)

Δ9-THC (trace) – TRPV2 possible agonist; CB1/CB2; peripheral engagement only.

β-Caryophyllene 

TRPV1/TRPA1 indirect modulation
CB2 agonist; mild PPAR-γ activity.

Menthol / Peppermint Extract

Menthol – TRPM8 agonist, TRPA1 modulator; indirectly influences CB1/CB2. Drives rapid, clean cooling.

Cat's Claw

Indirect TRP modulation; NF-κB pathway.

Evening Primrose Oil

Indirect TRP modulation; eicosanoid pathway modulation.
Quality & Safety Data

INCI Ingredient Information

Certified Full Spectrum CBD Cream

Professional Glide & Cooling Sensation

CBD Cooling Cream’s adaptive emulsion provides a consistent, medium-level glide ideal for focused manual techniques, offering 3–6 minutes of workable slip per pea-sized application under moderate pressure. It transitions smoothly to a clean finish without residue, buildup on tools, or oily transfer to fabrics.

Full-Spectrum Hemp Extract

Contains naturally occurring cannabinoids: CBD, CBDV, CBG, and trace Δ9-THC (<0.3%)

Cannabinoid potency per batch CoA:

 ~4,843mg total cannabinoids per 100g Micronized for even dispersion in mCNB2 matrix, supporting maximum surface contact.

Barrier-Friendly Botanicals

Aloe, oat kernel flour, allantoin, bisabol, and shea butter help maintain skin comfort and hydration during and after repeated handling.

Cooling Complex

Menthol, camphor essential oil, and supporting botanical actives provide a smooth cooling arc without the harsh sting of high-dose menthol gels.

Quality Assurance & Compliance

Every batch of CBD Cooling Cream is subjected to rigorous triple-tier lab testing—screening for potency, heavy metals, microbials, and pesticides—to ensure dependable, professional-grade quality. Formulated with THC-free, micronized CBD and CBG isolates, it delivers superior topical absorption to help ease tension and support everyday musculoskeletal recovery without risk of psychoactivity or drug test concerns.

Enhanced with a soothing cooling effect, this advanced cream offers targeted relief designed for active lifestyles and recovery routines.

LegitScript Certification and GMP manufacturing uphold the highest standards of compliance and safety. Full transparency is maintained through QR-coded batch test results. For in-depth details on safety protocols, certified lab data, and complete directions for use, please download the accompanying MSDS document.

INCI Ingredient Name

CAS Number(s)

Ingredient Type & Purpose

Aqua (Deionized Water)

7732‑18‑5

Solvent / vehicle

Aloe Barbadensis Leaf Juice

94349-62-9

Botanical skin soother, hydration support

Cannabis Sativa Extract

89958-21-4

Full-spectrum hemp extract (CBD, CBDV, CBG, trace THC)

Cannabidiol (CBD)

13956-29-1

Functional cannabinoid

Caprylic/Capric Triglyceride

73398-61-5

Lightweight emollient, slip enhancer

Isopropyl Palmitate

142-91-6

Emollient, penetration enhancer

Glyceryl Stearate SE

11099‑07‑3

Self‑emulsifying primary emulsifier

Camphor Essential Oil

8008-51-3

Mild warming/cooling sensory agent

Cetyl Alcohol

36653-82-4

Fatty alcohol, thickener, stabilizer

Stearic Acid

57-11-4

Emollient ester, improves slip & solubilizes functional functional ingredients

Menthol

89‑78‑1

Cooling agent / counter‑irritant

Glycerin (Vegetable)

56‑81‑5

Humectant, moisture binder

Propanediol

504‑63‑2

Humectant, solvent, penetration enhancer

Tocopherol (Vitamin E)

59‑02‑9

Antioxidant, protects oils & skin

Allantoin

97‑59‑6

Skin protectant, soothing agent

Avena Sativa (Oat) Kernel Flour

134134‑86‑4

Soothing colloidal oat, film‑former

Dimethicone

9006‑65‑9

Occlusive silicone emollient, skin protectant

Xanthan Gum

11138‑66‑2

Rheology/viscosity modifier, stabiliser

Sodium Hyaluronate (Hyaluronic Acid)

9067‑32‑7

Ultra low molecular  weight humectant, tissue hydration

Aristoflex AVC

91081‑14‑0

Pre‑neutralised polymer thickener & texturiser

Butyrospermum Parkii (Shea) Butter

194043-92-0

Emollient, skin conditioning

Tetrasodium EDTA

64‑02‑8

Chelating agent, boosts preservative efficacy

Capsicum  Annuum  Fruit  Extract

84625‑29‑6

Warming counter‑irritant, micro‑circulation support

Rosmarinus Officinalis (Rosemary)  Leaf Oil

8000‑25‑7

Antioxidant essential oil, fragrance

Uncaria Tomentosa Extract

223748-12-7

Botanical extract

Lavandula  Angustifolia (Lavender)  Oil

8000‑28‑0

Calming aroma, soothing and calming properties

Eucalyptus  Globulus Leaf  Oil

8000‑48‑4

Cooling essential oil, penetration enhancer

Beta‑Caryophyllene

87‑44‑5

Terpene synergist, anti‑inflammatory

Eugenol

97‑53‑0

Phenolic fragrance component, antiseptic

Oenothera Biennis (Evening Primrose) Oil

90028-66-3

Skin conditioning oil

Chamomilla Recutita (Matricaria) Flower Extract

84082-60-0

Skin soothing botanical

Calendula Officinalis Flower Extract

84776-23-8

Skin conditioning botanical

Pelargonium Graveolens Flower Extract

90082-51-2

Botanical skin soother

Calendula Officinalis Flower Extract

84776-23-8

Skin conditioning botanical

Sesamum Indicum (Sesame) Seed Oil

8008-74-0

Emollient

CBD Cooling Product FAQ

CBD Cooling Cream FAQ

What is CBD Cooling Cream?

A premium, full-spectrum cooling cream designed for adults seeking targeted comfort and skin-friendly hydration in one elegant formula.

How is it different from other creams?

Instead of high-menthol burn, you get a smooth, balanced cooling sensation paired with the full benefits of hemp cannabinoids—plus a non-greasy finish that won’t stain clothes.

CBD (primary), with CBDV, CBG, and compliant trace Δ9-THC (<0.3%).

Each batch contains CBD as the primary cannabinoid, with measurable levels of CBDV and CBG, plus compliant trace Δ9-THC (<0.3%).

How do I use it?

Massage one full pump into the target area as needed (safe for routine use). Wash your hands after use. 

Will it cause me to fail a drug test?

No the CBD Cooling Cream topical will not cause you to fail a drug test.